Comment
doi: 10.1016/j.neuron.2009.11.027.
Taking off the SOCS: cytokine signaling spurs regeneration
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- PMID: 20005813
- DOI: 10.1016/j.neuron.2009.11.027
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Comment
Taking off the SOCS: cytokine signaling spurs regeneration
Neuron.
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Free article
Abstract
Strategies to improve function after CNS injuries must contend with the failure of axons to regrow after transection in adult mammals. In this issue of Neuron, Smith et al. provide an important advance by demonstrating that SOCS3 acts as a key negative regulator of adult optic nerve regeneration.
Comment on
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SOCS3 deletion promotes optic nerve regeneration in vivo.Neuron. 2009 Dec 10;64(5):617-23. doi: 10.1016/j.neuron.2009.11.021. Neuron. 2009. PMID: 20005819 Free PMC article.
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