Comment
doi: 10.1016/j.molcel.2009.11.026.
Checkpoint Mec-tivation comes in many flavors
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- PMID: 20005837
- DOI: 10.1016/j.molcel.2009.11.026
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Checkpoint Mec-tivation comes in many flavors
Mol Cell.
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Free article
Abstract
In this issue of Molecular Cell, Navadgi-Patil and Burgers show that the budding yeast Mec1 kinase is activated by DNA damage through two distinct Ddc1-mediated mechanisms during G1 and G2 phases of the cell cycle.
Comment on
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The unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms.Mol Cell. 2009 Dec 11;36(5):743-53. doi: 10.1016/j.molcel.2009.10.014. Mol Cell. 2009. PMID: 20005839 Free PMC article.
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