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Review
. 2010 Mar;64(3):177-83.
doi: 10.1016/j.biopha.2009.09.017. Epub 2009 Nov 18.

Histological substrate of human atrial fibrillation

Cristina Chimenti  1 , Matteo A Russo, Angelo Carpi, Andrea Frustaci
Affiliations
Review

Histological substrate of human atrial fibrillation

Cristina Chimenti et al. Biomed Pharmacother. 2010 Mar.

Abstract

Histologic and ultrastructural examination of atrial tissue regarding the main entities responsible of human atrial fibrillation, is reported. The pathologic changes deriving from various disorders, like degenerative, inflammatory, ischemic diseases as well as from cardiac aging and hormonal imbalance are analysed. Structural changes associated with lone atrial fibrillation and investigated by atrial biopsy are also described, as being able to provide useful information on the disease's etiology, prognosis and treatment.

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