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Review
. 2010 Feb 12;1217(7):941-52.
doi: 10.1016/j.chroma.2009.11.079. Epub 2009 Dec 2.

Chiral silica-based monoliths in chromatography and capillary electrochromatography

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Review

Chiral silica-based monoliths in chromatography and capillary electrochromatography

Dorothee Wistuba. J Chromatogr A. .

Abstract

Chiral-modified silica-based monoliths have become well-established stationary phases for both high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The silica-based monoliths were fabricated either in situ in the capillaries for nano-HPLC and CEC or in a mould for "conventional" HPLC. The present review summarizes the chiral modification of silica monoliths and the recent development in the field of enantioselective separations by nano-HPLC and CEC.

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