Clinical trials: how to cope with medical needs, ethics and timelines
- PMID: 20007619
- DOI: 10.1136/ard.2009.120733
Clinical trials: how to cope with medical needs, ethics and timelines
Comment on
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The time has come to limit the placebo period in rheumatoid arthritis trials to 3 months: a systematic comparison of 3- and 6-month response rates in trials of biological agents.Ann Rheum Dis. 2010 Jan;69(1):186-92. doi: 10.1136/ard.2009.115832. Ann Rheum Dis. 2010. PMID: 19773287
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A new design for registration trials in rheumatoid arthritis allowing secondary head-to-head comparisons with standard of care treatment including biologicals.Ann Rheum Dis. 2010 Jan;69(1):4-6. doi: 10.1136/ard.2009.110007. Ann Rheum Dis. 2010. PMID: 20007620
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