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Comment
. 2009 Dec 11;326(5959):1491-2.
doi: 10.1126/science.1183604.

Plant science. DNA binding made easy

Daniel F Voytas  1 , J Keith Joung
Affiliations
Comment

Plant science. DNA binding made easy

Daniel F Voytas et al. Science. .
No abstract available

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Figures

Code is broken.
Code is broken.
The DNA binding domain of bacterial TAL effectors contains tandem repeats (about 17; shown in blue, pink, yellow, and green for AvrBs3) of amino acids (34 or 35). The repeat is highly conserved, except for residues at positions 12 and 13 (shown within each repeat; H, histidine; D, aspartic acid; N, asparagine; G, glycine; I, isoleucine; S, serine). The code relates diamino acids in the repeat unit to nucleotides (T, thymine; A, adenine; C, cytosine) in the DNA target.
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