Review
doi: 10.4161/psb.4.11.9755.
Epub 2009 Nov 7.
Plant defensins: defense, development and application
Affiliations
- PMID: 20009545
- PMCID: PMC2819505
- DOI: 10.4161/psb.4.11.9755
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Review
Plant defensins: defense, development and application
Plant Signal Behav.
2009 Nov.
Abstract
Plant defensins are small, highly stable, cysteine-rich peptides that constitute a part of the innate immune system primarily directed against fungal pathogens. Biological activities reported for plant defensins include antifungal activity, antibacterial activity, proteinase inhibitory activity and insect amylase inhibitory activity. Plant defensins have been shown to inhibit infectious diseases of humans and to induce apoptosis in a human pathogen. Transgenic plants overexpressing defensins are strongly resistant to fungal pathogens. Based on recent studies, some plant defensins are not merely toxic to microbes but also have roles in regulating plant growth and development.
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References
-
- Taylor K, Barran PE, Dorin JR. Structure-activity relationships in beta-defensin peptides. Biopolymers. 2008;90:1–7. - PubMed
-
- Lay FT, Anderson MA. Defensins—components of the innate immune system in plants. Curr Prot Pept Sci. 2005;6:85–101. - PubMed
-
- Wong JH, Xia L, Ng TB. A review of defensins of diverse origins. Curr Protein Peptide Sci. 2007;8:446–459. - PubMed
-
- Stotz HU, Spence B, Wang Y. A defensin from tomato with dual function in defense and development. Plant Mol Biol. 2009;71:131–143. - PubMed
-
- Colilla FJ, Rocher A, Mendez E. Gamma-Purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. FEBS Lett. 1990;270:191–194. - PubMed
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