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Review
. 2010 Feb;58(2):277-81.
doi: 10.2310/JIM.0b013e3181c9b2d4.

Randomized clinical trials in stroke research

Chul Ahn  1 , Daniel Ahn
Affiliations
Review

Randomized clinical trials in stroke research

Chul Ahn et al. J Investig Med. 2010 Feb.

Abstract

A randomized clinical trial is widely regarded as the most rigorous study design to determine the efficacy of intervention because spurious causality and bias associated with other experimental designs can be avoided. The purpose of this article is to provide clinicians and clinical researchers the types of randomized clinical trials used in stroke studies and to discuss the advantages and the limitations for each type of randomized stroke clinical trials.

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Figures

Figure 1
Figure 1
Parallel Design
Figure 2
Figure 2
Run-in Design
Figure 3
Figure 3
Randomized Consent Design
See this image and copyright information in PMC

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