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Case Reports
. 2009:2009:931057.
doi: 10.1155/2009/931057.

Ectopic calcification as discernible manifestation in neonates with pseudohypoparathyroidism type 1a

Masanori Adachi  1 , Koji Muroya, Yumi Asakura, Yoichi Kondoh, Jun Ishihara, Tomonobu Hasegawa
Affiliations
Case Reports

Ectopic calcification as discernible manifestation in neonates with pseudohypoparathyroidism type 1a

Masanori Adachi et al. Int J Endocrinol. 2009.

Abstract

The diagnosis of pseudohypoparathyroidism type 1a (PHP1a) is challenging, because both the osteodystrophy, such as brachydactyly and round face, and the symptomatic hypocalcemia usually develop beyond infancy. Although ectopic calcification may be an early sign of PHP1a, there are no systematic reviews regarding the time of its appearance. We here report on two PHP1a patients who presented with subcutaneous calcification in neonatal period.

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Figures

Figure 1
Figure 1
Skull radiograph of patient 1 taken on 13 days of age. White arrow indicates the calcification at right parietal region.
Figure 2
Figure 2
Skull CT image of patient 2 taken at 7 months of age. Calcification at right parietal region is evident.
See this image and copyright information in PMC

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