Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Aug;20(3):190-202.
doi: 10.1055/s-2007-984863.

Total mesorectal excision: what are we doing?

Affiliations

Total mesorectal excision: what are we doing?

David B Stewart et al. Clin Colon Rectal Surg. 2007 Aug.

Abstract

The introduction of total mesorectal excision (TME) for rectal cancer has reduced local recurrence rates and improved oncologic outcomes, although complication rates such as anastomotic leak have also been a consequence. With the advent of neoadjuvant therapy for rectal cancer, many are questioning how this development may change the role of TME. This review presents a history of how TME evolved and a description of this technique. Complication rates, the impact of neoadjuvant therapy on local recurrence, variations of TME such as nerve-sparing proctectomy and cancer-specific mesorectal excision, and a review of functional outcomes for various methods of reconstruction are presented.

Keywords: Total mesorectal excision; rectal cancer; recurrence; review article; surgical technique.

PubMed Disclaimer

Similar articles

Cited by

References

    1. See the National Cancer Institute's Surveillance Epidemiology, and end results (SEER) Available at: http://www.seer.cancer.gov. Accessed September 2006. Available at: http://www.seer.cancer.gov
    1. Heald R J, Husband E M, Ryall R D. Recurrence and survival after total mesorectal excision for rectal cancer. Lancet. 1986;1:1479–1482. - PubMed
    1. Chapuis P, Bokey L, Fahrer M, et al. Mobilization of the rectum: anatomic concepts and the bookshelf revisited. Dis Colon Rectum. 2002;45:1–9. - PubMed
    1. Jonnesco T. In: Poirier P, Charpy A, editor. Traite d'anatomie Humaine. Vol. IV. 2nd ed. Paris: Masson et Cie; 1901. Appareil digestif. pp. 372–373.
    1. Gerota D. Die lymphgefasse des rectums und des anus. Archive fur Anatomie und Physiologie. Anatomische Abtheilung. 1895:240–256.