Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 May;19(2):78-87.
doi: 10.1055/s-2006-942348.

Anal melanoma

Marc Singer  1 , Matthew G Mutch
Affiliations

Anal melanoma

Marc Singer et al. Clin Colon Rectal Surg. 2006 May.

Abstract

Anal melanoma is rare and aggressive malignancy. Patients commonly present with advanced, even metastatic disease. Unlike cutaneous melanoma, anal melanoma has no known risk factors. Surgical excision remains the cornerstone of therapy. There are no long-term survivors of stage II or III disease; therefore, early diagnosis and treatment remain crucial. There are no trials definitively proving abdominal perineal resection (APR) or wide local excision (WLE) to yield superior long-term survival. APR may offer a higher rate of local control, whereas WLE offers a much less morbid operation. Adjuvant chemotherapy, interferon, and radiation may offer some benefit.

Keywords: Melanoma; abdominoperineal resection; anal; malignancy; wide local excision.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Roumen R MH. Anorectal melanoma in the Netherlands: a report of 63 patients. Eur J Surg Oncol. 1996;22:598–601. - PubMed
    1. Bullard K M, Tuttle T M, Rothenberger D A, et al. Surgical therapy for anorectal melanoma. J Am Coll Surg. 2003;196:206–211. - PubMed
    1. Molino D, Perrotti P, Antropoli C, et al. Primary anorectal melanoma. Chir Ital. 2000;52:329–334. - PubMed
    1. Chang A E, Karnell L H, Menck H R. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. Cancer. 1998;83:1664–1678. - PubMed
    1. Pack G T, Lenson N, Gerber D M. Regional distribution of moles and melanomas. Arch Surg. 1952;65:862–870. - PubMed