Reoperation for recurrent colorectal cancer
- PMID: 20011326
- PMCID: PMC2780113
- DOI: 10.1055/s-2006-956445
Reoperation for recurrent colorectal cancer
Abstract
Recurrence of colorectal carcinoma represents a significant challenge. As the majority of recurrences involve more than just the anastomosis, surgical resection is ordinarily a major undertaking. Curative resection may require resection of other organs and structures, resulting in complex reconstructive procedures and substantial morbidity. In addition, carefully selected patients with distant metastases to sites such as the liver and lungs may also undergo potentially curative resection. Long-term survival following curative surgery for recurrence, however, ranges from only 15 to 40%. In addition to resection for curative intent, some patients may benefit from palliative procedures designed to relieve symptoms. Surgery alone is not usually sufficient therapy in these patients. Chemotherapy and radiation therapy play a vital adjunctive role in the management of recurrent disease. This article strives to review the risk factors and patterns of recurrence, selection of individuals for resection of recurrent disease, and outcomes of surgical procedures.
Keywords: Colorectal neoplasm; metastatic; recurrence; surgery.
References
-
- Fuzun M, Terzi C, Sokmen S, Unek T, Haciyanli M. Potentially curative resection for locoregional recurrence of colorectal cancer. Surg Today. 2004;34:907–912. - PubMed
-
- Meyers M, Sasson A, Sigurdson E. Locoregional strategies for colorectal hepatic metastasis. Clin Colorectal Cancer. 2003;3:34–44. - PubMed
-
- Bowne W, Lee B, Wong W, et al. Operative salvage for locoregional recurrent colon cancer after curative resection: an analysis of 100 cases. Dis Colon Rectum. 2005;48:897–909. - PubMed
-
- Devesa J, Morales V, Enriquez J. Colorectal cancer: the basis for a comprehensive follow up. Dis Colon Rectum. 1988;31:636–652. - PubMed
-
- Waldron R, Donovan I. Clinical follow up and treatment of locally recurrent colorectal cancer. Dis Colon Rectum. 1987;30:428–430. - PubMed
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