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. 2009 Dec;23(12):811-5.
doi: 10.1155/2009/536860.

Predictors of medication adherence in pediatric inflammatory bowel disease patients at the Stollery Children's Hospital

L Kitney  1 , J M Turner, D Spady, B Malik, W El-Matary, R Persad, H Q Huynh
Affiliations

Predictors of medication adherence in pediatric inflammatory bowel disease patients at the Stollery Children's Hospital

L Kitney et al. Can J Gastroenterol. 2009 Dec.

Abstract
in English, French

Background: Patients with inflammatory bowel disease (IBD) often do not take their medications as prescribed.

Objective: To examine self-reported adherence rates in IBD patients at the Stollery Children's Hospital (Edmonton, Alberta) and to determine predictors of medication adherence.

Methods: A survey was mailed to 212 pediatric IBD patients of the Stollery Children's Hospital. A chart review was completed for those who returned the survey.

Results: A total of 119 patients completed the survey. The nonresponders were significantly older than responders (14.5 years versus 13.2 years; P=0.032). The overall adherence rate was 80%. Nonadherence was associated with older age (14.6 years versus 13.0 years; P=0.04), longer disease duration (5.0 years versus 3.1 years; P=0.004) and reported use of herbal medications (40.0% versus 13.6%; P=0.029). The most common reasons reported for missing medications were forgetfulness, feeling better and too many medications. In addition, patients reported being more likely to take anti-inflammatory medications and less likely to take herbal medicines.

Conclusion: Identified predictors of nonadherence such as age, disease duration and use of herbal treatments may enable the development of specific strategies to improve adherence in adolescents with IBD.

HISTORIQUE :: Souvent, les personnes atteintes d’une maladie inflammatoire de l’intestin (MII) ne prennent pas leurs médicaments tels qu’ils leur sont prescrits.

OBJECTIF :: Examiner les taux d’observance autodéclarés chez des patients atteints d’une MII du Stollery Children’s Hospital d’Edmonton, en Alberta, et déterminer les prédicteurs d’observance des médicaments.

MÉTHODOLOGIE :: On a posté un sondage à 212 patients pédiatriques atteints d’une MII du Stollery Children’s Hospital. On a effectué une étude des dossiers des patients qui ont remis le sondage.

RÉSULTATS :: Au total, 119 patients ont répondu au sondage. Les nonrépondants étaient beaucoup plus âgés que les répondants (14,5 ans par rapport à 13,2 ans, P=0,032). Le taux d’observance totale s’établissait à 80 %. La non-observance s’associait à l’âge (14,6 ans par rapport à 13,0 ans, P=0,04), à une plus longue durée de la maladie (5,0 ans par rapport à 3,1 ans, P=0,04) et à l’utilisation déclarée de plantes médicinales (40,0 % par rapport à 13,6 %, P=0,029). Les principales raisons invoquées pour ne pas prendre les médicaments étaient l’oubli, le fait de se sentir mieux et le fait de prendre trop de médicaments. De plus, les patients ont déclaré être plus susceptibles de prendre des médicaments anti-inflammatoires et moins susceptibles de prendre des plantes médicinales.

CONCLUSION :: Les prédicteurs établis de non-observance comme l’âge, la durée de la maladie et le recours à des plantes médicinales peuvent favoriser l’élaboration de stratégies précises pour améliorer l’observance des adolescents atteints d’une MII.

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References

    1. Day AS, Whitten KE, Bohane TD. Use of complementary and alternative medicines by children and adolescents with inflammatory bowel disease. J Paediatr Child Health. 2004;40:681–4. - PubMed
    1. Heuschkel R, Afzal N, Wuerth A, et al. Complementary medicine use in children and young adults with inflammatory bowel disease. Am J Gastroenterol. 2002;97:382–8. - PubMed
    1. Bernal I, Domenech E, Garcia-Planella, et al. Medication-taking behavior in a cohort of patients with inflammatory bowel disease. Dig Dis Sci. 2006;51:2165–9. - PubMed
    1. Sewitch MJ, Leffondre K, Dobkin PL. Clustering patients according to health perceptions: Relationships to psychosocial characteristics and medication nonadherence. J Psychosom Res. 2004;56:323–32. - PubMed
    1. Ediger JP, Walker JR, Graff L, et al. Predictors of medication adherence in inflammatory bowel disease. Am J Gastroenterol. 2007;102:1417–26. - PubMed

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