Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2010 Feb:14 Suppl 1:S67-74.
doi: 10.1007/s11605-009-1020-6. Epub 2009 Dec 10.

Is there a role for anything other than a Nissen's operation?

Affiliations
Meta-Analysis

Is there a role for anything other than a Nissen's operation?

Martin Fein et al. J Gastrointest Surg. 2010 Feb.

Abstract

Background: The Nissen fundoplication is the most frequently applied antireflux operation worldwide. The aim of this review was to compare laparoscopic Nissen with partial fundoplication.

Methods: Nine randomized trials comparing several types of wraps were analyzed, four for the comparison Nissen vs. Toupet and five for the comparison Toupet or Nissen vs. anterior fundoplication. Similar comparisons in nonrandomized studies were also included.

Results: Dysphagia rates and reflux recurrence were not related to preoperative esophageal persistalsis independent of the selected procedure. Overall, Nissen fundoplication revealed slightly better reflux control, but was associated with more side effects, such as early dysphagia and gas bloat. Advantages of an anterior approach were only reported by one group. A significantly higher reflux recurrence rate for anterior fundoplication was observed in all other comparisons.

Conclusion: Tailoring antireflux surgery according to esophageal motility is not indicated. At present, the relevant factor for selection of a Nissen or Toupet fundoplication is personal experience. Anterior fundoplication offers less effective long-term reflux control.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Gut. 1997 Mar;40(3):381-5 - PubMed
    1. Br J Surg. 2008 Jan;95(1):57-63 - PubMed
    1. Surg Endosc. 2008 Jan;22(1):21-30 - PubMed
    1. Surg Endosc. 2001 Apr;15(4):344-52 - PubMed
    1. Chirurg. 2007 Jan;78(1):35-9 - PubMed

LinkOut - more resources