The rat: a model used in biomedical research
- PMID: 20013222
- DOI: 10.1007/978-1-60327-389-3_1
The rat: a model used in biomedical research
Abstract
The rat evokes fear and disgust in a large percentage of people around the world. Yet, other people are fascinated by this amazing creature that is raised as a pet, has an important place in several religions, and is a prominent model for biomedical research. This book focuses on a variety of methodologies that can be used in this remarkable model. This chapter sets the stage by providing a perspective on why the rat remains an important model in biomedical research.
Similar articles
-
Impact of genomics on research in the rat.Genome Res. 2005 Dec;15(12):1717-28. doi: 10.1101/gr.3744005. Genome Res. 2005. PMID: 16339370 Review.
-
Getting resourceful.Nat Struct Mol Biol. 2008 Aug;15(8):767. doi: 10.1038/nsmb0808-767. Nat Struct Mol Biol. 2008. PMID: 18679427 No abstract available.
-
Text-mining approaches in molecular biology and biomedicine.Drug Discov Today. 2005 Mar 15;10(6):439-45. doi: 10.1016/S1359-6446(05)03376-3. Drug Discov Today. 2005. PMID: 15808823 Review.
-
Sequencing of the rat genome and databases.Methods Mol Biol. 2010;597:33-53. doi: 10.1007/978-1-60327-389-3_3. Methods Mol Biol. 2010. PMID: 20013224
-
The chick embryo: hatching a model for contemporary biomedical research.Bioessays. 2009 Apr;31(4):459-65. doi: 10.1002/bies.200800168. Bioessays. 2009. PMID: 19274658 Review.
Cited by
-
Genome resource banking of biomedically important laboratory animals.Theriogenology. 2012 Nov;78(8):1653-65. doi: 10.1016/j.theriogenology.2012.08.012. Epub 2012 Sep 13. Theriogenology. 2012. PMID: 22981880 Free PMC article.
-
Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes.J Biomed Sci. 2020 Aug 2;27(1):84. doi: 10.1186/s12929-020-00673-8. J Biomed Sci. 2020. PMID: 32741357 Free PMC article. Review.
-
Volumetric atlas of the rat inner ear from microCT and iDISCO+ cleared temporal bones.PeerJ. 2025 May 26;13:e19512. doi: 10.7717/peerj.19512. eCollection 2025. PeerJ. 2025. PMID: 40444285 Free PMC article.
-
A simple, quantitative method using alginate gel to determine rat colonic tumor volume in vivo.Comp Med. 2014 Apr;64(2):128-34. Comp Med. 2014. PMID: 24674588 Free PMC article.
-
Creation of X-linked Alport syndrome rat model with Col4a5 deficiency.Sci Rep. 2021 Oct 21;11(1):20836. doi: 10.1038/s41598-021-00354-y. Sci Rep. 2021. PMID: 34675305 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources