Review
doi: 10.1007/s11427-009-0158-5.
Epub 2009 Dec 17.
Circulating miRNA and cancer diagnosis
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- PMID: 20016968
- DOI: 10.1007/s11427-009-0158-5
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Review
Circulating miRNA and cancer diagnosis
Sci China C Life Sci.
2009 Dec.
Abstract
miRNAs are a class of small RNA molecules with regulatory function, and play an important role in tumor development and progression. It has been demonstrated that tumor-derived miRNAs exist in the circulating nucleic acids of cancer patients. This phenomenon implies that detection of the circulating miRNA may be an effective method for non-invasive diagnosis of cancer. In this review, we summarize the applications of the circulating miRNA as biomarkers in cancer diagnosis, as well as the latest research progress in this area.
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