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Review
. 2010 Feb;52(1):117-40.
doi: 10.1111/j.1600-0757.2009.00308.x.

Herpesviral-bacterial interactions in periodontal diseases

Jørgen Slots
Review

Herpesviral-bacterial interactions in periodontal diseases

Jørgen Slots. Periodontol 2000. 2010 Feb.
No abstract available

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Figures

Figure 1
Figure 1
 Schematic representation of herpesvirus replication. A herpesvirus virion initiates infection by fusing specific viral glycoproteins on the viral envelope with cellular receptors on the cell surface. After entering the cytoplasm, capsid is transported to the nuclear pore where viral DNA is released into the nucleus. Viral transcription and translation occur in 3 phases; immediate early, early, and late. Immediate early proteins are involved in viral transcriptional regulation and in mobilizing the cellular transcriptional machinery. Early proteins facilitate viral DNA replication. Late proteins are structural proteins of the virus that form empty capsids. Viral DNA is packaged into preformed capsids in the nucleus. Viral glycoproteins and tegument proteins are incorporated into the cellular membrane, and capsids become enveloped to form virions. Virions are transported via the endoplasmic reticulum, and infectious virions can either remain cell associated, spread to uninfected cells via virus‐induced fusion, or can be released from the cell by exocytosis or by cell lysis.
Figure 2
Figure 2
 Herpesviral‐bacterial model of periodontitis.
See this image and copyright information in PMC

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References

    1. Abramson JS, Mills EL. Depression of neutrophil function induced by viruses and its role in secondary microbial infections. Rev Infect Dis 1988: 10: 326–341. - PubMed
    1. Abramson JS, Wheeler JG. Virus‐induced neutrophil dysfunction: role in the pathogenesis of bacterial infections. Pediatr Infect Dis J 1994: 13: 643–652. - PubMed
    1. Adjei AA, Armah HB, Gbagbo F, Boamah I, Adu‐Gyamfi C, Asare I. Seroprevalence of HHV‐8, CMV, and EBV among the general population in Ghana, West Africa. BMC Infect Dis 2008: 8: 111. - PMC - PubMed
    1. Al‐Otaibi LM, Al‐Sulaiman MH, Teo CG, Porter SR. Extensive oral shedding of human herpesvirus 8 in a renal allograft recipient. Oral Microbiol Immunol 2009: 24: 109–115. - PubMed
    1. Alho OP. Viral infections and susceptibility to recurrent sinusitis. Curr Allergy Asthma Rep 2007: 5: 477–481. - PMC - PubMed

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