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Comment
. 2009;13(6):1008.
doi: 10.1186/cc8169. Epub 2009 Nov 2.

Death by acid rain: VAP or EXIT?

Kentigern Thorburn  1 , Andrew Darbyshire
Affiliations
Comment

Death by acid rain: VAP or EXIT?

Kentigern Thorburn et al. Crit Care. 2009.

Abstract

Ventilator-associated pneumonia (VAP) is a new (nosocomial) lower respiratory tract infection diagnosed in mechanically ventilated patients 48 or more hours after intubation. There is no gold standard for establishing the diagnosis and its pathogenesis is iatrogenic and multifactorial. Gastro-oesophageal reflux is common in mechanically ventilated children, but its role in VAP remains speculative. VAP is associated with increased mortality and morbidity, prolonged duration of ventilation and hospital stay, and escalated costs of hospitalisation. VAP 'bundles' are championed as the antidote.

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References

    1. Abdel Gawad TA, El-Hodhod MA, Ibrahim HM, Michael YW. Gastroesophageal reflux in mechanically ventilated pediatric patients and its relationship to ventilator-associated pneumonia. Crit Care. 2009;13:R164. doi: 10.1186/cc8134. - DOI - PMC - PubMed
    1. Valles J, Pobo A, Garcia-Esquinol O, Marsical D, Ral T, Fernandez R. Excess ICU mortality attributable to VAP: the role of early and late onset. Intensive Care Med. 2007;33:1363–1368. doi: 10.1007/s00134-007-0721-0. - DOI - PubMed
    1. Diaz E, Munoz E, Agbaht K, Rello J. Management of ventilator-associated pneumonia caused by multi-resistant bacteria. Curr Opin Crit Care. 2007;13:45–50. doi: 10.1097/MCC.0b013e3280121816. - DOI - PubMed
    1. Foglia E, Meier MD, Elward A. Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients. Clin Microbiol Rev. 2007;20:409–425. doi: 10.1128/CMR.00041-06. - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention. Criteria for Defining Nosocomial Pneumonia. http://www.cdc.gov/ncidod/hip/NNIS/members/pneumonia/Final/PneumoCriteri...

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