Review
doi: 10.1016/j.arcped.2009.11.016.
Epub 2009 Dec 16.
[Diffuse intrinsic brain stem glioma in children: current treatment and future directions]
[Article in
French]
Affiliations
- PMID: 20018494
- DOI: 10.1016/j.arcped.2009.11.016
Item in Clipboard
Review
[Diffuse intrinsic brain stem glioma in children: current treatment and future directions]
[Article in
French]
Arch Pediatr.
2010 Feb.
Abstract
Despite the numerous clinical trials undertaken, the prognosis of children with diffuse brain stem glioma remains very poor. This review examines the different strategies for the treatment of malignant brain stem glioma such as radiation therapy, concurrent radiochemotherapy, and classical cytotoxic drugs, with a particular focus on the novel targeted and antiangiogenic drugs recently introduced in pediatric oncology. The strategy using integrin inhibitors is discussed.
Copyright 2009 Elsevier Masson SAS. All rights reserved.
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