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Comment

. 2010 Feb;176(2):540-1.

doi: 10.2353/ajpath.2010.090856. Epub 2009 Dec 17.

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

Massimo Tabaton¹, George Perry, Xiongwei Zhu, Hyoung-gon Lee, Gemma Casadesus, Mark A Smith

Affiliations

PMID: 20019185
PMCID: PMC2808061
DOI: 10.2353/ajpath.2010.090856

Comment

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

Massimo Tabaton et al. Am J Pathol. 2010 Feb.

. 2010 Feb;176(2):540-1.

doi: 10.2353/ajpath.2010.090856. Epub 2009 Dec 17.

Authors

Massimo Tabaton¹, George Perry, Xiongwei Zhu, Hyoung-gon Lee, Gemma Casadesus, Mark A Smith

Affiliation

¹ Department of Neuroscience, University of Genova, Genova, Italy.

PMID: 20019185
PMCID: PMC2808061
DOI: 10.2353/ajpath.2010.090856

Abstract

This commentary discusses the role of memantine in treating Alzheimer Disease.

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Comment on

Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.
Martinez-Coria H, Green KN, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM. Martinez-Coria H, et al. Am J Pathol. 2010 Feb;176(2):870-80. doi: 10.2353/ajpath.2010.090452. Epub 2009 Dec 30. Am J Pathol. 2010. PMID: 20042680 Free PMC article.

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References

1. McShane R, Areosa Sastre A, Minakaran N. Memantine for dementia. Cochrane Database Syst Rev. 2006;(2):CD003153–CD003154. - PubMed
1. van Marum RJ. Update on the use of memantine in Alzheimer’s disease. Neuropsychiatr Dis Treat. 2009;5:237–247. - PMC - PubMed
1. Martinez-Coria H, Green KN, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM. Memantine improves cognition and reduces Alzheimer’s-like neuropathology in transgenic mice, Am J Pathol. 2010;176:870–880. - PMC - PubMed
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