Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Mar;173(6):2116-9.
doi: 10.1128/jb.173.6.2116-2119.1991.

Tandem translation starts in the cheA locus of Escherichia coli

E C Kofoid  1 , J S Parkinson
Affiliations

Tandem translation starts in the cheA locus of Escherichia coli

E C Kofoid et al. J Bacteriol. 1991 Mar.

Abstract

The cheA locus of Escherichia coli encodes two protein products, CheAL and CheAS. The nucleotide sequences of the wild-type cheA locus and of two nonsense alleles confirmed that both proteins are translated in the same reading frame from different start points. These start sites were located on the coding sequence by direct determination of the amino-terminal sequences of the two CheA proteins. Both starts are flanked by inverted repeats that may play a role in regulating the relative expression rates of the CheA proteins through alternative mRNA secondary structures.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Eur J Biochem. 1967 Mar;1(1):80-91 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5370-4 - PubMed
    1. J Bacteriol. 1982 Jul;151(1):106-13 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Mar;85(5):1403-7 - PubMed

Publication types