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. 2010 Jan 7;46(1):21-43.
doi: 10.1039/b913845e. Epub 2009 Oct 30.

Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

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Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

Richard J Payne et al. Chem Commun (Camb). .

Abstract

A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.

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