Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes
- PMID: 2002467
- DOI: 10.1021/jm00107a001
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes
Similar articles
-
Drug-membrane interactions: significance for medicinal chemistry.Curr Med Chem. 2010;17(17):1795-809. doi: 10.2174/092986710791111233. Curr Med Chem. 2010. PMID: 20345343 Review.
-
[Drug permeation through artificial lipid membranes. 17. The mechanism of ion pair transport].Pharmazie. 1984 Jun;39(6):401-3. Pharmazie. 1984. PMID: 6091156 German.
-
Depth-dependent fluorescent quenching in micelles and membranes.Biochim Biophys Acta. 1985 Jun 12;822(1):43-62. doi: 10.1016/0304-4157(85)90003-6. Biochim Biophys Acta. 1985. PMID: 3890948 Review. No abstract available.
-
Parabolic structure-activity relationships: a simple pharmacokinetic model.J Pharm Pharmacol. 1982 Nov;34(11):746-9. doi: 10.1111/j.2042-7158.1982.tb06217.x. J Pharm Pharmacol. 1982. PMID: 6129312 No abstract available.
-
Tethered bilayer lipid membranes (tBLMs): interest and applications for biological membrane investigations.Biochimie. 2014 Dec;107 Pt A:135-42. doi: 10.1016/j.biochi.2014.06.021. Epub 2014 Jul 4. Biochimie. 2014. PMID: 24998327 Review.
Cited by
-
Fat feeding potentiates the diabetogenic effect of dexamethasone in Wistar rats.Int Arch Med. 2008 May 23;1(1):7. doi: 10.1186/1755-7682-1-7. Int Arch Med. 2008. PMID: 18500989 Free PMC article.
-
A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists.ACS Med Chem Lett. 2021 Jul 19;12(8):1230-1237. doi: 10.1021/acsmedchemlett.1c00305. eCollection 2021 Aug 12. ACS Med Chem Lett. 2021. PMID: 34413952 Free PMC article.
-
A fast and reliable spectroscopic method for the determination of membrane--water partition coefficients of organic compounds.Lipids. 2001 Jan;36(1):89-96. doi: 10.1007/s11745-001-0673-0. Lipids. 2001. PMID: 11214736
-
Lateral diffusion rates of lipid, water, and a hydrophobic drug in a multilamellar liposome.Biophys J. 2003 Sep;85(3):1734-40. doi: 10.1016/S0006-3495(03)74603-7. Biophys J. 2003. PMID: 12944288 Free PMC article.
-
Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.Drug Des Discov. 1992;9(1):49-67. Drug Des Discov. 1992. PMID: 1457698 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Other Literature Sources
Medical