Comparative Study
doi: 10.1016/0022-2836(91)90867-6.
A large number of tRNA genes are symmetrically located in fission yeast centromeres
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- PMID: 2002498
- DOI: 10.1016/0022-2836(91)90867-6
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Comparative Study
A large number of tRNA genes are symmetrically located in fission yeast centromeres
J Mol Biol.
.
Abstract
We report here that the fission yeast centromere regions in the three chromosomes contain no less than 36 symmetrically arranged tRNA-coding sequences, and many of them are located within the inner inverted regions that are thought to be essential for the centromere function. There are 11 different species of tRNA-coding sequences, and four of them are identical to those previously known in this organism. This high-density distribution of tRNA genes in the centromere regions is surprising, as the fission yeast centromeres were thought to form transcriptionally inactive structures.
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