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. 2010 Mar;53(3):217-23.
doi: 10.1002/ajim.20788.

Occupational factors and risk of Parkinson's disease: A population-based case-control study

Jordan A Firestone  1 , Jessica I Lundin, Karen M Powers, Terri Smith-Weller, Gary M Franklin, Phillip D Swanson, W T Longstreth Jr, Harvey Checkoway
Affiliations

Occupational factors and risk of Parkinson's disease: A population-based case-control study

Jordan A Firestone et al. Am J Ind Med. 2010 Mar.

Abstract

Background: Parkinson's disease (PD) has been associated with various workplace factors, but the evidence is inconsistent.

Objective: To estimate the risk of PD associated with various jobs and workplace exposures.

Methods: We conducted a population-based, case-control study of 404 incident PD cases and 526 age and sex-matched controls, collecting self-reported work histories including job titles and exposures to various industrial toxicants. Relative risks of PD from these exposures were estimated with odds ratios (OR) and 95% confidence intervals (CI) using logistic regression.

Results: Risk was not significantly affected by farming work, by metal work, or by exposure to pesticides, metals, or solvents.

Conclusions: These findings do not provide support for the hypothesis that workplace factors affect the risk of PD.

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Conflict of interest statement

The authors report no conflicts of interest.

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