doi: 10.1128/JVI.65.4.2146-2148.1991.
Immunoglobulin A mediation of murine nasal anti-influenza virus immunity
Affiliations
- PMID: 2002558
- PMCID: PMC240095
- DOI: 10.1128/JVI.65.4.2146-2148.1991
Item in Clipboard
Immunoglobulin A mediation of murine nasal anti-influenza virus immunity
J Virol.
1991 Apr.
Abstract
Most mice which have recovered from influenza virus infection are immune to reinfection with the same influenza virus. This immunity could be abrogated by the intranasal instillation of anti-immunoglobulin A (anti-IgA) but not of anti-IgG or anti-IgM antiserum. Thus, IgA is the major, if not the sole, mediator of nasal immunity to influenza virus in immunocompetent mice.
Similar articles
-
Protection and recovery in influenza virus-infected mice immunosuppressed with anti-IgM.J Immunol. 1985 Feb;134(2):1230-5. J Immunol. 1985. PMID: 2981265
-
Role of IgA versus IgG in the control of influenza viral infection in the murine respiratory tract.J Immunol. 2004 Aug 1;173(3):1978-86. doi: 10.4049/jimmunol.173.3.1978. J Immunol. 2004. PMID: 15265932
-
Impairment of mucosal immunity by total parenteral nutrition: requirement for IgA in murine nasotracheal anti-influenza immunity.J Immunol. 2001 Jan 15;166(2):819-25. doi: 10.4049/jimmunol.166.2.819. J Immunol. 2001. PMID: 11145655
-
Studies on the usefulness of intranasal inactivated influenza vaccines.Vaccine. 2010 Aug 31;28(38):6393-7. doi: 10.1016/j.vaccine.2010.05.019. Epub 2010 May 20. Vaccine. 2010. PMID: 20493820 Review.
-
Mucosal IgA responses in influenza virus infections; thoughts for vaccine design.Vaccine. 2012 Aug 31;30(40):5893-900. doi: 10.1016/j.vaccine.2012.04.109. Epub 2012 Jul 24. Vaccine. 2012. PMID: 22835738 Review.
Cited by
-
Vaccination with M2e-based multiple antigenic peptides: characterization of the B cell response and protection efficacy in inbred and outbred mice.PLoS One. 2011;6(12):e28445. doi: 10.1371/journal.pone.0028445. Epub 2011 Dec 13. PLoS One. 2011. PMID: 22180783 Free PMC article.
-
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge.Cell Rep. 2021 Dec 14;37(11):110112. doi: 10.1016/j.celrep.2021.110112. Epub 2021 Nov 24. Cell Rep. 2021. PMID: 34863353 Free PMC article.
-
Coadministration of DNA encoding interleukin-6 and hemagglutinin confers protection from influenza virus challenge in mice.J Virol. 1998 Feb;72(2):1704-8. doi: 10.1128/JVI.72.2.1704-1708.1998. J Virol. 1998. PMID: 9445082 Free PMC article.
-
Antirotavirus immunoglobulin A neutralizes virus in vitro after transcytosis through epithelial cells and protects infant mice from diarrhea.J Virol. 1998 Apr;72(4):2708-14. doi: 10.1128/JVI.72.4.2708-2714.1998. J Virol. 1998. PMID: 9525588 Free PMC article.
-
Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection.Virology. 2015 Feb;476:124-133. doi: 10.1016/j.virol.2014.12.007. Epub 2014 Dec 24. Virology. 2015. PMID: 25543963 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
