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Multicenter Study
. 2009 Dec 21:8:58.
doi: 10.1186/1476-069X-8-58.

Fine particulate air pollution and its components in association with cause-specific emergency admissions

Antonella Zanobetti  1 , Meredith Franklin, Petros Koutrakis, Joel Schwartz
Affiliations
Multicenter Study

Fine particulate air pollution and its components in association with cause-specific emergency admissions

Antonella Zanobetti et al. Environ Health. .

Abstract

Background: Although the association between exposure to particulate matter and health is well established, there remains uncertainty as to whether certain chemical components are more harmful than others. We explored whether the association between cause-specific hospital admissions and PM(2.5) was modified by PM(2.5) chemical composition.

Methods: We estimated the association between daily PM(2.5) and emergency hospital admissions for cardiac causes (CVD), myocardial infarction (MI), congestive heart failure (CHF), respiratory disease, and diabetes in 26 US communities, for the years 2000-2003. Using meta-regression, we examined how this association was modified by season- and community-specific PM(2.5) composition, controlling for seasonal temperature as a surrogate for ventilation.

Results: For a 10 microg/m3 increase in 2-day averaged PM(2.5) concentration we found an increase of 1.89% (95% CI: 1.34- 2.45) in CVD, 2.25% (95% CI: 1.10- 3.42) in MI, 1.85% (95% CI: 1.19- 2.51) in CHF, 2.74% (95% CI: 1.30- 4.2) in diabetes, and 2.07% (95% CI: 1.20- 2.95) in respiratory admissions. The association between PM2.5 and CVD admissions was significantly modified when the mass was high in Br, Cr, Ni, and Na(+), while mass high in As, Cr, Mn, OC, Ni, and Na(+) modified MI, and mass high in As, OC, and SO(4)(2-) modified diabetes admissions. For these species, an interquartile range increase in their relative proportion was associated with a 1-2% additional increase in daily admissions per 10 microg/m(3) increase in mass.

Conclusions: We found that PM(2.5) mass higher in Ni, As, and Cr, as well as Br and OC significantly increased its effect on hospital admissions. This result suggests that particles from industrial combustion sources and traffic may, on average, have greater toxicity.

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Figures

Figure 1
Figure 1
Community and season-specific proportions of species to PM2.5 mass for 6 selected species: Arsenic, Bromine, Chromium, Organic Carbon, Sodium, and Nickel. The seasons are: "black triangle" = winter; "black square" = spring; "star" = summer; "black circle" = autumn.
Figure 2
Figure 2
Los Angeles: wind rose of the relationship between Na+ concentrations in ng/m3 and wind direction.
See this image and copyright information in PMC

References

    1. Atkinson RW, Anderson HR, Sunyer J, Ayres J, Baccini M, Vonk JM, Boumghar A, Forastiere F, Forsberg B, Touloumi G, Schwartz J, Katsouyanni K. Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air Pollution and Health: a European Approach. American journal of respiratory and critical care medicine. 2001;164:1860–1866. - PubMed
    1. Le Tertre A, Medina S, Samoli E, Forsberg B, Michelozzi P, Boumghar A, Vonk JM, Bellini A, Atkinson R, Ayres JG, Sunyer J, Schwartz J, Katsouyanni K. Short-term effects of particulate air pollution on cardiovascular diseases in eight European cities. Journal of epidemiology and community health. 2002;56:773–779. doi: 10.1136/jech.56.10.773. - DOI - PMC - PubMed
    1. Burnett RT, Smith-Doiron M, Stieb D, Cakmak S, Brook JR. Effects of particulate and gaseous air pollution on cardiorespiratory hospitalizations. Archives of environmental health. 1999;54:130–139. doi: 10.1080/00039899909602248. - DOI - PubMed
    1. Schwartz J. Air pollution and hospital admissions for heart disease in eight U.S. counties. Epidemiology. 1999;10:17–22. - PubMed
    1. Schwartz J, Morris R. Air pollution and hospital admissions for cardiovascular disease in Detroit, Michigan. American journal of epidemiology. 1995;142:23–35. - PubMed

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