Are current drug development programmes realising the full potential of new agents? Tyrosine kinase inhibitors
- PMID: 20030876
- PMCID: PMC2797704
- DOI: 10.1186/bcr2443
Are current drug development programmes realising the full potential of new agents? Tyrosine kinase inhibitors
References
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- Baselga J, Rischin D, Ranson M, Calvert H, Raymond E, Kieback DG, Kaye SB, Gianni L, Harris A, Bjork T, Averbuch SD, Feyereislova A, Swaisland H, Rojo F, Albanell J. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J Clin Oncol. 1839;20:4292–4302. doi: 10.1200/JCO.2002.03.100. - DOI - PubMed
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- Baselga J, Yano S, Giaccone G, Nakagawa K, Tamura T, Douillard J, Nishiwaki Y, Vansteenkiste JF, Kudou S, Rischin D, Eek RW, Averbuch S, Macleod A, Feyereislova A, Dong R-P, Fukuoka M. Initial results from a phase II trial of ZD-1839 (IRESSA) as second and third line monotherapy for patients with advanced non-small cell lung cancer (IDEAL-1) Program and abstracts of the 2001 AACR-NCI-EORTC International Conference - Molecular Targets and Cancer Therapeutics. October 29-November 2, 2001; Miami Beach, Florida. Abstract 630A.
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