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Case Reports
. 2010 Feb;48(2):623-5.
doi: 10.1128/JCM.02397-09. Epub 2009 Dec 23.

Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California

Jennifer Le  1 , Mariana Castanheira, David S Burgess, Barbara McKee, Raza Iqbal, Ronald N Jones
Affiliations
Case Reports

Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California

Jennifer Le et al. J Clin Microbiol. 2010 Feb.

Abstract

Carbapenems (CARBs) are the primary treatment for infections caused by extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae strains. Production of a serine carbapenemase, KPC, is increasing alarmingly in the United States and is probably contributing to CARB resistance rates. We describe the clinical and molecular characteristics of four infections caused by KPC-3 K. pneumoniae strains.

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References

    1. Castanheira, M., R. E. Mendes, P. R. Rhomberg, and R. N. Jones. 2008. Rapid emergence of blaCTX-M among Enterobacteriaceae in U.S. medical centers: molecular evaluation from the MYSTIC Program (2007). Microb. Drug Resist. 14:211-216. - PubMed
    1. Castanheira, M., L. N. Woosley, R. E. Mendes, L. Deshpande, and R. N. Jones. 2008. Increasing prevalence of KPC-producers as an emerging resistance mechanism among carbapenem non-susceptible isolates: report from the sentry antimicrobial surveillance program, abstr. C1-126. Abstr. 48th Annu. Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)-Infect. Dis. Soc. Am. (IDSA) 46th Annu. Meet. American Society for Microbiology and Infectious Diseases Society of America, Washington, DC.
    1. Goldfarb, D., S. B. Harvey, K. Jessamine, P. Jessamine, B. Toye, and M. Desjardins. 2009. Detection of plasmid-mediated KPC-producing Klebsiella pneumoniae in Ottawa, Canada: evidence of intrahospital transmission. J. Clin. Microbiol. 47:1920-1922. - PMC - PubMed
    1. Hidron, A. I., J. R. Edwards, J. Patel, T. C. Horan, D. M. Sievert, D. A. Pollock, and S. K. Fridkin. 2008. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Dis. Control and Prevention, 2006-2007. Infect. Control Hosp. Epidemiol. 29:996-1011. - PubMed
    1. Kitchel, B., J. K. Rasheed, J. B. Patel, A. Srinivasan, S. Navon-Venezia, Y. Carmeli, A. Motakefi, and C. G. Giske. 2009. Molecular epidemiology of KPC-producing Klebsiella pneumoniae in the United States: clonal expansion of multilocus sequence type 258. Antimicrob. Agents Chemother. 53:3365-3370. - PMC - PubMed

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