Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010 Jan;11(1):4-5.
doi: 10.1038/embor.2009.265.

Opening a new DOR to autophagy

Jaeline Spowart  1 , Julian J Lum
Affiliations
Comment

Opening a new DOR to autophagy

Jaeline Spowart et al. EMBO Rep. 2010 Jan.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Incorporation of DOR into the autophagy pathway. The autophagy pathway is explained in detail in the main text. Upon cellular stress, DOR is exported from the nucleus and possibly aids the beclin 1/Vps34 complex in the nucleation of the autophagosome. LC3 and GATE16 localize to the autophagsome during its formation and form a complex with DOR. DOR is detached from the autophagsome before it becomes an autolysosome, in which the targeted cellular components are degraded.
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

References

    1. Baumgartner BG et al. (2007) PLoS ONE 2: e1183. - PMC - PubMed
    1. Byfield MP et al. (2005) J Biol Chem 280: 33076–33082 - PubMed
    1. Congcong H, Klionsky DJ (2007) Autophagy 3: 271–274 - PubMed
    1. Juhasz G (2008) J Cell Bio 4: 655–666 - PMC - PubMed
    1. Levine B et al. (2008) Autophagy 4: 600–606 - PMC - PubMed

LinkOut - more resources