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Comment
. 2010 Jan;11(1):4-5.
doi: 10.1038/embor.2009.265.

Opening a new DOR to autophagy

Jaeline Spowart  1 , Julian J Lum
Affiliations
Comment

Opening a new DOR to autophagy

Jaeline Spowart et al. EMBO Rep. 2010 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Incorporation of DOR into the autophagy pathway. The autophagy pathway is explained in detail in the main text. Upon cellular stress, DOR is exported from the nucleus and possibly aids the beclin 1/Vps34 complex in the nucleation of the autophagosome. LC3 and GATE16 localize to the autophagsome during its formation and form a complex with DOR. DOR is detached from the autophagsome before it becomes an autolysosome, in which the targeted cellular components are degraded.
See this image and copyright information in PMC

Comment on

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