Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010:612:393-409.
doi: 10.1007/978-1-60761-362-6_27.

Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus

Nassima Fodil-Cornu  1 , Michal Pyzik, Silvia M Vidal
Affiliations

Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus

Nassima Fodil-Cornu et al. Methods Mol Biol. 2010.

Abstract

Genetically distinct inbred strains of mice that differ in their susceptibility to mouse cytomegalovirus (MCMV) are invaluable for dissecting complex host-pathogen interactions. Their study has allowed the identification of host-resistance loci, including several activating NK cell receptors of major histocompatibility complex (MHC) class I. In this chapter, we provide a practical guide to the genetic mapping and functional characterization of NK cell receptors that control innate immunity against MCMV via specific recognition of infected cells.

PubMed Disclaimer

MeSH terms

LinkOut - more resources