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Randomized Controlled Trial
. 2010 Jan 7;16(1):63-8.
doi: 10.3748/wjg.v16.i1.63.

Z-line examination by the PillCam SB: prospective comparison of three ingestion protocols

Ignacio Fernandez-Urien  1 , Erika Borobio, Inmaculada Elizalde, Rebeca Irisarri, Juan Jose Vila, Jesus Maria Urman, Javier Jimenez
Affiliations
Randomized Controlled Trial

Z-line examination by the PillCam SB: prospective comparison of three ingestion protocols

Ignacio Fernandez-Urien et al. World J Gastroenterol. .

Abstract

Aim: To evaluate the Z-line visualization by the PillCam SB2 using three different ingestion protocols.

Methods: Ninety consecutive patients undergoing small bowel capsule endoscopy (SBCE) between January and May 2008 were included in the study. They swallowed the capsule in the standing (Group A = 30), supine (Group B = 30) and right supine positions (Group C = 30). Baseline patient characteristics, difficulties in capsule ingestion, esophageal transit times (ETT) and Z-line visualization were noted.

Results: No significant differences were found between the groups with regard to baseline patient characteristics, ingestion difficulties and complete SB examinations (P > 0.05). At least 1 frame of the Z-line was detected in 15.8%, 46.7% and 90% of patients in groups A, B and C, respectively (P < 0.001). The average number of Z-line images was 0.21 +/- 0.53, 3.23 +/- 6.59 and 5.53 +/- 7.55 and the mean % of the Z-line detected was 71.3, 25.1 and 8.3, in groups A, B and C, respectively (both P < 0.001). ETT times were longer in the supine group followed by the right supine and the standing groups (median of 237 s vs 64 s and 39 s, respectively; P < 0.001).

Conclusion: Z-line visualization in patients undergoing SBCE can be accurately achieved in most cases when the capsule is swallowed in the right supine position.

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Figures

Figure 1
Figure 1
Capsule ingestion in the standing position (A: group A), supine position (B: group B) and right supine position (C: group C).
Figure 2
Figure 2
Z-line visualization by the PillCam™ SB.
See this image and copyright information in PMC

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References

    1. Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy. Nature. 2000;405:417. - PubMed
    1. Appleyard M, Glukhovsky A, Swain P. Wireless-capsule diagnostic endoscopy for recurrent small-bowel bleeding. N Engl J Med. 2001;344:232–233. - PubMed
    1. Lewis BS, Swain P. Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: Results of a pilot study. Gastrointest Endosc. 2002;56:349–353. - PubMed
    1. Appleyard M, Fireman Z, Glukhovsky A, Jacob H, Shreiver R, Kadirkamanathan S, Lavy A, Lewkowicz S, Scapa E, Shofti R, et al. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions. Gastroenterology. 2000;119:1431–1438. - PubMed
    1. Costamagna G, Shah SK, Riccioni ME, Foschia F, Mutignani M, Perri V, Vecchioli A, Brizi MG, Picciocchi A, Marano P. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology. 2002;123:999–1005. - PubMed

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