[Postinfarction cardiac remodeling--clinical consequences]

Abstract

Despite the considerable progress in the setting of invasive and pharmacological treatment still in about 20-30% patients with myocardial infarction in long-term observation an unfavourable post-infarction remodeling along with development of LV dilatation is to be seen. The heart forms the structural and functional unity, thus morphological changes due to cardiac post-infarction remodeling process are accompanied by systolic and diastolic myocardial dysfunction, which in consequence may lead to appearance of heart failure. In recent years our knowledge regarding causative factors of post-infarction cardiac remodeling has been remarkably widening and in the light of accumulating data indicating the possibility of LV remodeling regression, elaboration of the new specific-orientated methods of counteracting its uneventful consequenses is a matter of time.