Review
[Colorectal carcinoma and DNA methylation]
[Article in
Chinese]
Affiliations
- PMID: 20045925
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Review
[Colorectal carcinoma and DNA methylation]
[Article in
Chinese]
Zhong Nan Da Xue Xue Bao Yi Xue Ban.
2009 Dec.
Abstract
Epigenetic regulation involved in eukaryotic gene expression plays an important role in the progression of colorectal cancer. Colorectal cancer epigenetics is evolved in DNA methylation which is associated with the activation of oncogene and inactivation of tumor suppressor gene. The potential reversibility of DNA methylation offers exciting opportunities for therapy and diagnosis of colorectal carcinoma.
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