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. 2010 Jan;58(1):110-2.
doi: 10.1248/cpb.58.110.

Synthesis and configurational stability of (S)- and (R)-deuteriothalidomides

Takeshi Yamamoto  1 , Etsuko Tokunaga, Shuichi Nakamura, Norio Shibata, Takeshi Toru
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Free article

Synthesis and configurational stability of (S)- and (R)-deuteriothalidomides

Takeshi Yamamoto et al. Chem Pharm Bull (Tokyo). 2010 Jan.
Free article

Abstract

3'-Deuteriothalidomide was synthesized and found to be configurationally five times more stable than thalidomide toward racemization at physiological pH.

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