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. 2010 Jan;6(1):10-1.
doi: 10.1038/nrrheum.2009.235.

Therapy: Hydroxychloroquine in SLE: old drug, new perspectives

Thomas Dörner

Therapy: Hydroxychloroquine in SLE: old drug, new perspectives

Thomas Dörner. Nat Rev Rheumatol. 2010 Jan.

Erratum in

  • Nat Rev Rheumatol. 2010 Mar;6(3):118

Abstract

Antimalarial agents have long been used in the treatment of autoimmune diseases, despite uncertainty regarding the exact mechanisms underlying their various effects. Growing evidence that these drugs offer protection from major infections could stimulate more research into these mechanisms, with possible implications for therapy.

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Conflict of interest statement

The author declares no competing financial interests.

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References

    1. James JA. Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus. Lupus. 2007;16:401–409. doi: 10.1177/0961203307078579. - DOI - PubMed
    1. Kaiser R, Cleveland C, Criswell LA. Risk and protective factors for thrombosis in systemic lupus erythematosus: results from a large, multi-ethnic cohort. Ann. Rheum. Dis. 2009;68:238–241. doi: 10.1136/ard.2008.093013. - DOI - PMC - PubMed
    1. Ruiz-Irastorza G. Effect of antimalarials on thrombosis and survival in patients with systemic lupus erythematosus. Lupus. 2006;15:577–583. doi: 10.1177/0961203306071872. - DOI - PubMed
    1. Siso A. Previous antimalarial therapy in patients diagnosed with lupus nephiritis: influence on outcomes and survival. Lupus. 2008;17:281–288. doi: 10.1177/0961203307086503. - DOI - PubMed
    1. Tsakonas E. A long-term study of hydroxychloroquine withdrawal on exacerbations in systemic lupus erythematosus. The Canadian Hydroxychloroquine Study Group. Lupus. 1998;7:80–85. doi: 10.1191/096120398678919778. - DOI - PubMed

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