Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Jul-Aug;70(4):415-22.
doi: 10.4103/0250-474X.44587.

Herbal excipients in novel drug delivery systems

Herbal excipients in novel drug delivery systems

A Shirwaikar et al. Indian J Pharm Sci. 2008 Jul-Aug.

Abstract

The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.

Keywords: Polysaccharides; controlled delivery; volatile oils.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Structure of alginic acid.
Fig. 2
Fig. 2
Structures of (A) amylopectin or α- amylase and (B) β-amylose.
Fig. 3
Fig. 3
Structure of guar gum.
Fig. 4
Fig. 4
Structure of xanthan gum.
Fig. 5
Fig. 5
Structures of A. menthol, B. cineole, C. carvone and D.limonene.

References

    1. USP Subcommittee on excipients. Pharm Forum. 1992;18:4387.
    1. Sinha VR, Rachna K. Polysaccharides in colon specific drug delivery. Int J Pharm. 2001;224:19–38. - PubMed
    1. Sungthongjeen S, Pitaksuteepong T, Somsiri A, Sriamornsak P. Studies on pectins as potential hydrogel matrices for controlled release drug delivery. Drug Develop Ind Pharm. 1999;12:1271–6. - PubMed
    1. Tho I, Sande SA, Kleinebudde P. Pectinic acid: A novel excipient for production of pellets by extrusion/spheronisation: Preliminary studies. Eur J Pharm Biopharm. 2002;54:95–9. - PubMed
    1. Giunchedi P, Conte U, Chetoni P, Saettone MF. Pectin microspheres as ophthalmic carriers for piroxicam: Evaluation in vitro and in vivo in albino rabbits. Eur J Pharm Sci. 1999;9:1–7. - PubMed

LinkOut - more resources