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. 2009;54(1):46-8.
doi: 10.4103/0019-5154.48986.

Malignant transformation of actinic keratoses to squamous cell carcinoma in an albino

Vijaya Sivalingam Ramalingam  1 , Ramapriya Sinnakirouchenan, Devinder Mohan Thappa
Affiliations

Malignant transformation of actinic keratoses to squamous cell carcinoma in an albino

Vijaya Sivalingam Ramalingam et al. Indian J Dermatol. 2009.

Abstract

A 25-year-old male, who was a known case of oculocutaneous albinism presented to us with right inguinal swellings of six months' duration. He gave a preceding history of a similar lump in the right thigh, which was excised at the Chennai Government Hospital. He was diagnosed to have oculocutaneous albinism with actinic keratoses, with multiple squamous cell carcinomas (with metastatic deposits in the right inguinal region) and cutaneous horns. The case is reported to highlight preventive aspects in the management of albinos.

Keywords: Albinism; actinic keratoses; cutaneous horns; squamous cell carcinomas.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Albino showing actinic keratoses lesions over the chest
Figure 2
Figure 2
Malignant transformation of actinic keratoses to squamous cell carcinoma
Figure 3
Figure 3
Lower leg developing cutaneous horns
See this image and copyright information in PMC

References

    1. Lookingbill DP, Lookingbill GL, Leppard B. Actinic damage and skin cancer in albinos in northern Tanzania. J Am Acad Dermatol. 1995;32:653–8. - PubMed
    1. King RA, Oetting WS. Albinism. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB, editors. Fitzpatrick's dermatology in general medicine. 5th ed. New York: McGraw Hill; 1999. pp. 925–34.
    1. Bolognia JL, Shapiro PE. Albinism and other disorders of hypopigmentation. In: Arndt KA, Leboit PE, Robinson JK, Wintroub BU, editors. Cutaneous medicine and surgery: An integrated program in dermatology. 1st ed. New York: WB Saunders; 1996.
    1. Schulze KE, Rapini RP, Duvic M. Malignant melanoma in oculocutaneous albinism. Arch Dermatol. 1989;125:1583–5. - PubMed
    1. Fu W, Cockerell CJ. The Actinic (Solar) keratosis: A 21 st century perspective. Arch Dermatol. 2003;139:66–70. - PubMed