Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Apr;95(4):684-5.
doi: 10.3324/haematol.2009.018333. Epub 2010 Jan 6.

Similar favorable outcome of pegfilgrastim overdose in patients with different age and underlying disease

Case Reports

Similar favorable outcome of pegfilgrastim overdose in patients with different age and underlying disease

Carlo Dufour et al. Haematologica. 2010 Apr.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
WBC, ANC and pegfilgrastim serum level after overdose in patient 1. Outcome of WBC and ANC in patient 1 after the injection of a pegfilgrastim overdose 9.37-fold greater than scheduled. Pegfilgrastim serum concentration is shown on the right y-axis.
Figure 2.
Figure 2.
WBC, ANC and pegfilgrastim serum level after overdose in patient 2. Outcome of WBC and ANC in patient 2 after the injection of a pegfilgrastim overdose 8-fold greater than prescribed. Pegfilgrastim serum concentration is shown on the right y-axis.

References

    1. Green MD, Koelbl H, Baselga J, Galid A, Guillem V, Gascon P, et al. A randomized double-blind multicenter phase III study of fixed-dose single-administration pegfilgrastim versus daily filgrastim in patients receiving myelosuppressive chemotherapy. Ann Oncol. 2003;14(1):29–35. - PubMed
    1. Bruns I, Steidl U, Fischer JC, Czibere A, Kobbe G, Raschke S, et al. Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor. Haematologica. 2008;93(3):347–55. - PubMed
    1. Beaupain B, Leblanc T, Reman O, Hermine O, Vannier JP, Suarez F, et al. French SCN Registry, Service d'Hémato Oncologie Pédiatrique. Is pegfilgrastim safe and effective in congenital neutropenia? An analysis of the French Severe Chronic Neutropenia registry. Pediatr Blood Cancer. 2009;53(6):1068–73. - PubMed
    1. Fioredda F, Calvillo M, Lanciotti M, Lanza T, Giunti L, Castagnola E, et al. Pegfilgrastim in children with Severe Congenital Neutropenia. Pediatr Blood Cancer. 2009 In press. - PubMed
    1. Merli F, Bertini M, Luminari S, Mozzana R, Botto B, Liberati AM, et al. Long term results of a randomized study performed by Intergruppo Italiano Linfomi comparing Mini-CEOP vs P-VEBEC in elderly patients with diffuse large B-cell lymphoma. Leuk Lymphoma. 2007;48(2):367–73. - PubMed