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. 2009 Oct;6(10):2526-33.
doi: 10.3390/ijerph6102526. Epub 2009 Sep 28.

Epidemiological study of rickettsial infections in patients with hypertransaminemia in Madrid (Spain)

Lourdes Lledó  1 , Rosario González, María Isabel Gegúndez, María Beltrán, José Vicente Saz
Affiliations

Epidemiological study of rickettsial infections in patients with hypertransaminemia in Madrid (Spain)

Lourdes Lledó et al. Int J Environ Res Public Health. 2009 Oct.

Abstract

A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti-R. conorii IgG antibodies and 7% for R. typhi. PCR analysis was performed in patients with IgM antibodies. Among 143 healthy subjects from the general population, seven (4.9%) were positive for anti-R. conorii IgG antibodies, and 2.8% for R. typhi. These results show that anti-rickettsial antibodies are more commonly detected in patients with hypertransaminemia than in healthy people.

Keywords: Rickettsiae; Spain; hypertransaminemia; liver dysfunction; prevalence.

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Figure 1.
Figure 1.
The geographical area of the study.
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