Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Feb 20;217(4):595-8.
doi: 10.1016/0022-2836(91)90515-8.

Transcriptional enhancer in the vicinity of a replication origin within the 5' region of the chicken alpha-globin gene domain

S V Razin  1 , Y S Vassetzky Jr, A I Kvartskhava, N F Grinenko, G P Georgiev
Affiliations

Transcriptional enhancer in the vicinity of a replication origin within the 5' region of the chicken alpha-globin gene domain

S V Razin et al. J Mol Biol. .

Abstract

A transcriptional enhancer is located near a replication origin within an upstream area of chicken domain of alpha-globin genes. Minimal region possessing enhancer properties is located about 4 kb upstream from the alpha-pi gene. Addition of the neighbouring 500 base-pair DNA fragment, including the constitutive DNase I hypersensitive site, increases the enhancer activity approximately twofold.

PubMed Disclaimer

LinkOut - more resources