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. 2009 Dec 2:2:9129.
doi: 10.1186/1757-1626-2-9129.

Adenosquamous carcinoma of the pancreas, a rare tumor entity: a case report

Pavlos Lampropoulos  1 , Georgios Filippou, Evangelia Skafida, Thivi Vasilakaki, Nikolaos Paschalidis, Spiros Rizos
Affiliations

Adenosquamous carcinoma of the pancreas, a rare tumor entity: a case report

Pavlos Lampropoulos et al. Cases J. .

Abstract

Introduction: Adenosquamous carcinoma of the pancreas is a rare variant of exocrine pancreatic tumor. This type of tumor is extremely rare as only few similar cases have been described in the literature.

Case presentation: We present a case of a 72 years old male patient who was admitted to the hospital complaining of epigastric pain and jaundice. Pancreatic carcinoma of the head was diagnosed and a pylorus preserving pancreaticoduodenectomy was performed.

Conclusion: This type of cancer is a very aggressive tumor followed by a dismisal prognosis. Multimodality therapy seems to be a reasonable approach but more studies are needed, to propose the most effective treatment.

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Figures

Figure 1
Figure 1
CT scan of the patient showing the tumor.
Figure 2
Figure 2
(H&E ×20) Adenosquamous carcinoma of the pancreas with area of necrosis.
Figure 3
Figure 3
(H&E ×40) Adenosquamous carcinoma of the pancreas.
Figure 4
Figure 4
(H&E ×100) Adenocarcinoma similar to ductal carcinoma.
Figure 5
Figure 5
(H&E ×200) Squamous cell carcinoma composed of irregular nests of polygonal cells with no gland formation.
Figure 6
Figure 6
(H&E ×100) Lymph node metastasis only from the squamous element.
Figure 7
Figure 7
(Ker7 ×100) Ker7 showed predilection for adenocarcinoma.
Figure 8
Figure 8
(CK5/6 ×100) The squamous component was strongly immunoreactive with CK5/6, while the glandular component was negative.
See this image and copyright information in PMC

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