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Case Reports
. 2010 Sep;9(3):331-4.
doi: 10.1007/s10689-009-9316-y.

Pregnancy after prophylactic total gastrectomy

Pardeep Kaurah  1 , Rebecca Fitzgerald, Sarah Dwerryhouse, David G Huntsman
Affiliations
Case Reports

Pregnancy after prophylactic total gastrectomy

Pardeep Kaurah et al. Fam Cancer. 2010 Sep.

Abstract

Hereditary diffuse gastric cancer is an autosomal dominant inherited cancer predisposition syndrome characterized by susceptibility to diffuse gastric and lobular breast cancers. Since current screening options for diffuse gastric cancer are ineffective, prophylactic total gastrectomy (PTG) is a recommended option for unaffected germline CDH1 mutation carriers. It is unknown whether pregnancy after surgery is possible or advisable due to potential maternal nutritional deficiencies. In this report we describe the pregnancy outcomes in three CDH1 mutation positive women after PTG and in a CDH1 mutation negative woman after total gastrectomy for early gastric cancer.

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References

    1. N Engl J Med. 2001 Jun 21;344(25):1904-9 - PubMed
    1. Surgery. 2001 Oct;130(4):612-7; discussion 617-9 - PubMed
    1. Arch Gynecol Obstet. 2008 May;277(5):381-8 - PubMed
    1. J Med Genet. 1999 Dec;36(12):873-80 - PubMed
    1. J Am Geriatr Soc. 1958 Feb;6(2):99-102 - PubMed

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