High-risk medulloblastoma: does c-myc amplification overrule histopathology?
- PMID: 20063409
- PMCID: PMC4517433
- DOI: 10.1002/pbc.22398
High-risk medulloblastoma: does c-myc amplification overrule histopathology?
Comment on
-
Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors.Pediatr Blood Cancer. 2010 Mar;54(3):369-76. doi: 10.1002/pbc.22339. Pediatr Blood Cancer. 2010. PMID: 19908297
Similar articles
-
MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group.Arch Pathol Lab Med. 2002 May;126(5):540-4. doi: 10.5858/2002-126-0540-MAMOAI. Arch Pathol Lab Med. 2002. PMID: 11958658
-
Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors.Pediatr Blood Cancer. 2010 Mar;54(3):369-76. doi: 10.1002/pbc.22339. Pediatr Blood Cancer. 2010. PMID: 19908297
-
Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases.Pediatr Blood Cancer. 2012 Sep;59(3):561-4. doi: 10.1002/pbc.24002. Epub 2011 Dec 6. Pediatr Blood Cancer. 2012. PMID: 22147345 Free PMC article.
-
Cytogenetics and molecular genetics of malignant gliomas and medulloblastoma.Brain Pathol. 1990 Sep;1(1):12-8. doi: 10.1111/j.1750-3639.1990.tb00633.x. Brain Pathol. 1990. PMID: 1669688 Review.
-
[Update on pediatric oncology].Bull Cancer. 1998 Jan;85(1):57-8. Bull Cancer. 1998. PMID: 9752350 Review. French. No abstract available.
Cited by
-
A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma.Cancers (Basel). 2021 Jan 21;13(3):387. doi: 10.3390/cancers13030387. Cancers (Basel). 2021. PMID: 33494392 Free PMC article.
-
The clinical implications of medulloblastoma subgroups.Nat Rev Neurol. 2012 May 8;8(6):340-51. doi: 10.1038/nrneurol.2012.78. Nat Rev Neurol. 2012. PMID: 22565209 Review.
-
cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome.J Neurooncol. 2013 Nov;115(2):249-59. doi: 10.1007/s11060-013-1221-4. Epub 2013 Aug 11. J Neurooncol. 2013. PMID: 23934175 Free PMC article.
References
-
- Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol. 2006;24:4202–4208. - PubMed
-
- Pfister S, Remke M, Benner A, et al. Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol. 2009;27:1627–1636. - PubMed
-
- Giangaspero F, Eberhart CG, Haapasalo H, et al. Medulloblastoma. In: Louis DN, Hirolo O, Wiester OD, Cavenee WK, editors. WHO classification of tumours of the central nervous system. Lyon, France: International Agency for Research on Cancer; 2007. pp. 132–140.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical