Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Dec 24;139(7):1220-2.
doi: 10.1016/j.cell.2009.12.016.

Integrins and mutant p53 on the road to metastasis

Galina Selivanova  1 , Johanna Ivaska
Affiliations
Free article

Integrins and mutant p53 on the road to metastasis

Galina Selivanova et al. Cell. .
Free article

Abstract

Understanding how tumor cells invade tissues is key to developing drugs to block metastasis. In this issue, Muller et al. (2009) report that a mutant form of the tumor suppressor p53 in cancer cells boosts the endocytic recycling of the adhesion molecule integrin alpha5beta1 and of epidermal growth factor receptor, promoting invasion and metastasis.

PubMed Disclaimer

LinkOut - more resources