A molecular sensor for the baroreceptor reflex?
- PMID: 20064383
- DOI: 10.1016/j.neuron.2009.12.020
A molecular sensor for the baroreceptor reflex?
Abstract
The reflex that provides rapid neural control of blood pressure is triggered by an unknown molecular pressure sensor. ASIC2, an ion channel in a family that includes a mechanosensor from C. elegans, is shown by Lu et al. in this issue of Neuron to be critical for this reflex in mice, perhaps because ASIC2 is the elusive pressure sensor.
2009 Elsevier Inc. All rights reserved.
Comment on
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The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation.Neuron. 2009 Dec 24;64(6):885-97. doi: 10.1016/j.neuron.2009.11.007. Neuron. 2009. PMID: 20064394 Free PMC article.
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