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. 2009 Dec 18;31(6):849-51.
doi: 10.1016/j.immuni.2009.12.002.

The multiple mechanisms of T cell receptor cross-reactivity

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Free article

The multiple mechanisms of T cell receptor cross-reactivity

Yiyuan Yin et al. Immunity. .
Free article

Abstract

The ability of a single T cell to recognize the diverse peptides it encounters is based on T cell receptor crossreactivity. In this issue of Immunity, Macdonald et al. (2009) and Borbulevych et al. (2009) provide new insights into the structural principles underlying this fundamental property of T cells.

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