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. 2010 Jan;82(1):128-35.
doi: 10.4269/ajtmh.2010.09-0346.

The epidemiology of dengue in the americas over the last three decades: a worrisome reality

José Luis San Martín  1 , Olivia Brathwaite, Betzana Zambrano, José Orlando Solórzano, Alain Bouckenooghe, Gustavo H Dayan, María G Guzmán
Affiliations

The epidemiology of dengue in the americas over the last three decades: a worrisome reality

José Luis San Martín et al. Am J Trop Med Hyg. 2010 Jan.

Abstract

We have reported the epidemic patterns of dengue disease in the Region of the Americas from 1980 through 2007. Dengue cases reported to the Pan American Health Organization were analyzed from three periods: 1980-1989 (80s), 1990-1999 (90s), and 2000-2007 (2000-7). Age distribution data were examined from Brazil, Venezuela, Honduras, and Mexico. Cases increased over time: 1,033,417 (80s) to 2,725,405 (90s) to 4,759,007 (2000-7). The highest concentrations were reported in the Hispanic Caribbean (39.1%) in the 80s shifting to the Southern Cone in the 90s (55%) and 2000-7 (62.9%). From 1980 through 1987, 242 deaths were reported compared with 1,391 during 2000-7. The most frequently isolated serotypes were DENV-1 and DENV-2 (90s) and DENV-2 and DENV-3 (2000-7). The highest incidence was observed among adolescents and young adults; dengue hemorrhagic fever incidence was highest among infants in Venezuela. Increasing dengue morbidity/mortality was observed in the Americas in recent decades.

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Figures

Figure 1.
Figure 1.
Number of dengue fever (DF) and dengue hemorrhagic fever (DHF) cases, Region of the Americas, 1980–2007.
Figure 2.
Figure 2.
Average dengue incidence per 100,000 by country, Region of the Americas, 1980–2007.
Figure 3.
Figure 3.
A, Countries with the highest number of dengue fever (DF) cases, Region of the Americas, 1980 and 2007. B, Countries with the highest number of dengue hemorrhagic fever (DHF) cases, Region of the Americas, 1980 and 2007.
Figure 4.
Figure 4.
Percentage of countries reporting serotypes 1–4 to the Pan American Health Organization by year, Region of the Americas, 1995–2007.
Figure 5.
Figure 5.
Incidence rates per 100,000 of dengue fever (DF) and dengue hemorrhagic fever (DHF) cases by age: (A) Brazil, (B) Mexico, (C) Honduras, and (D) Venezuela.
Figure 6.
Figure 6.
Monthly distribution of dengue cases: (A) Brazil, (B) Mexico, (C) Honduras, and (D) Venezuela.
See this image and copyright information in PMC

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