Emerging ventricular assist devices for long-term cardiac support
- PMID: 20065952
- DOI: 10.1038/nrcardio.2009.222
Emerging ventricular assist devices for long-term cardiac support
Abstract
Despite major advances in the treatment of heart failure over the past 2 decades improving the natural history of this condition, heart failure continues to be a major source of morbidity and mortality. Although availability of donor hearts for transplantation has declined over the past several years, innovations in ventricular assist device (VAD) technology has provided an alternative therapeutic option for patients with advanced heart failure. Initiated as a mechanical option to 'bridge' critically ill patients awaiting transplantation, VADs are being increasingly deployed as 'destination' devices to provide long-term support. With technical advances resulting in improved mechanical reliability, reduced postoperative morbidity and greater likelihood of patient acceptance, there is interest in expanding the applicability for destination VAD treatment beyond the current indication of severely ill patients who are not candidates for transplant. This Review examines the newer, third-generation VADs for mechanical cardiac support. These devices are at various stages of development and clinical investigation. One or more of these newer devices is likely to emerge as an important development in the treatment of patients with advanced heart failure.
Similar articles
-
Ventricular assist devices.Minerva Cardioangiol. 2013 Dec;61(6):691-700. Minerva Cardioangiol. 2013. PMID: 24253461 Review.
-
Heart failure and mechanical circulatory assist devices.Glob J Health Sci. 2013 May 14;5(5):11-9. doi: 10.5539/gjhs.v5n5p11. Glob J Health Sci. 2013. PMID: 23985102 Free PMC article. Review.
-
Ventricular assist devices: history, patient selection, and timing of therapy.J Cardiovasc Transl Res. 2009 Jun;2(2):159-67. doi: 10.1007/s12265-009-9098-5. Epub 2009 Mar 19. J Cardiovasc Transl Res. 2009. PMID: 20559983 Review.
-
Demystifying ventricular assist devices.Crit Care Nurs Q. 2011 Jul-Sep;34(3):200-7. doi: 10.1097/CNQ.0b013e31821c622d. Crit Care Nurs Q. 2011. PMID: 21670618
-
Ventricular assist devices in the adult.Crit Care Nurs Q. 2007 Apr-Jun;30(2):104-18; quiz 119-20. doi: 10.1097/01.CNQ.0000264254.90499.27. Crit Care Nurs Q. 2007. PMID: 17356352 Review.
Cited by
-
Hemolysis and Pulmonary Insufficiency following Right Ventricular Assist Device Implantation.Case Rep Transplant. 2012;2012:376384. doi: 10.1155/2012/376384. Epub 2012 Sep 26. Case Rep Transplant. 2012. PMID: 23213613 Free PMC article.
-
Development of a Double-Lumen Cannula for a Percutaneous RVAD.ASAIO J. 2015 Jul-Aug;61(4):397-402. doi: 10.1097/MAT.0000000000000227. ASAIO J. 2015. PMID: 25851314 Free PMC article.
-
High fidelity computational simulation of thrombus formation in Thoratec HeartMate II continuous flow ventricular assist device.Sci Rep. 2016 Dec 1;6:38025. doi: 10.1038/srep38025. Sci Rep. 2016. PMID: 27905492 Free PMC article.
-
Repair of abdominal aortic aneurysm in heart transplant patients: before or after left ventricular assist device implantation?Thorac Cardiovasc Surg. 2011 Mar;59(2):119-20. doi: 10.1055/s-0030-1250637. Epub 2011 Mar 7. Thorac Cardiovasc Surg. 2011. PMID: 21384309 Free PMC article.
-
Cardiogenic shock in ACS. Part 2: Role of mechanical circulatory support.Nat Rev Cardiol. 2012 Jan 10;9(4):195-208. doi: 10.1038/nrcardio.2011.205. Nat Rev Cardiol. 2012. PMID: 22231716 Review.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous